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1.
Int. j. cardiovasc. sci. (Impr.) ; 35(3): 364-372, May-June 2022. tab
Article in English | LILACS | ID: biblio-1375640

ABSTRACT

Abstract Background: Among the various pathologies that affect the elderly, Heart Failure (HF) stands out. Recently, an attempt has been made to verify the existence of cognitive impairment associated with HF. Objectives: To compare the cognitive performance of elderly people with heart failure with that of age-matched individuals without this pathology. Check the existence of marked impairment in some cognitive functions in the clinical group. Methods: The sample consisted of 78 elderly people, whose inclusion criterion was the presence of HF and no HF (control group); age over 60 years, both sexes, and any level of education. The control group consisted of 37 individuals (with a median age of 68 years - Interquartile range of 12) and the HF group, with 41 individuals (with a median age of 67 years - Interquartile range of 11). The subjects were matched in terms of education level, with a predominance of elderly people with 0 to 4 years of education (65.9% in the Clinical Group and 59.5% in the Control Group). Eleven neuropsychological tests covering cognitive functions were used: attention, language, memory, mood, and executive function. Statistical analysis was performed using SPSS software, version 23, with a significance level of 5%. The Chi-square test and the Mann-Whitney test were applied. Results: The results showed significant differences between the groups, mainly in executive functions, which include the ability to plan, switch, and recall previously stored information. Conclusion: Our study showed differences between the cognitive performance of elderly people with HF and elderly people without HF. The main alteration was found in the so-called executive functions, attention, and memory.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Attention , Aging , Executive Function , Cognitive Dysfunction , Heart Failure , Memory , Anxiety , Cross-Sectional Studies , Depression , Nervous System Diseases , Neuropsychology
3.
Faludi, André Arpad; Izar, Maria Cristina de Oliveira; Saraiva, José Francisco Kerr; Chacra, Ana Paula Marte; Bianco, Henrique Tria; Afiune Neto, Abrahão; Bertolami, Adriana; Pereira, Alexandre C; Lottenberg, Ana Maria; Sposito, Andrei C; Chagas, Antonio Carlos Palandri; Casella Filho, Antonio; Simão, Antônio Felipe; Alencar Filho, Aristóteles Comte de; Caramelli, Bruno; Magalhães, Carlos Costa; Negrão, Carlos Eduardo; Ferreira, Carlos Eduardo dos Santos; Scherr, Carlos; Feio, Claudine Maria Alves; Kovacs, Cristiane; Araújo, Daniel Branco de; Magnoni, Daniel; Calderaro, Daniela; Gualandro, Danielle Menosi; Mello Junior, Edgard Pessoa de; Alexandre, Elizabeth Regina Giunco; Sato, Emília Inoue; Moriguchi, Emilio Hideyuki; Rached, Fabiana Hanna; Santos, Fábio César dos; Cesena, Fernando Henpin Yue; Fonseca, Francisco Antonio Helfenstein; Fonseca, Henrique Andrade Rodrigues da; Xavier, Hermes Toros; Mota, Isabela Cardoso Pimentel; Giuliano, Isabela de Carlos Back; Issa, Jaqueline Scholz; Diament, Jayme; Pesquero, João Bosco; Santos, José Ernesto dos; Faria Neto, José Rocha; Melo Filho, José Xavier de; Kato, Juliana Tieko; Torres, Kerginaldo Paulo; Bertolami, Marcelo Chiara; Assad, Marcelo Heitor Vieira; Miname, Márcio Hiroshi; Scartezini, Marileia; Forti, Neusa Assumpta; Coelho, Otávio Rizzi; Maranhão, Raul Cavalcante; Santos Filho, Raul Dias dos; Alves, Renato Jorge; Cassani, Roberta Lara; Betti, Roberto Tadeu Barcellos; Carvalho, Tales de; Martinez, Tânia Leme da Rocha; Giraldez, Viviane Zorzanelli Rocha; Salgado Filho, Wilson.
Arq. bras. cardiol ; 109(2,supl.1): 1-76, ago. 2017. tab, graf
Article in Portuguese | LILACS | ID: biblio-887919
4.
Rev. bras. hipertens ; 22(2): 53-59, abr.-jun.2015.
Article in Portuguese | LILACS | ID: biblio-881263

ABSTRACT

A hipertensão arterial sistêmica (HAS) bem como o diabetes mellitus (DM) configuram-se como doenças de grande impacto na sociedade brasileira. Este trabalho teve como objetivo identificar o perfil da adesão dos usuários do Sistema de Cadastramento e Acompanhamento de Hipertensos e Diabéticos (HIPERDIA) aos tratamentos farmacológicos e não farmacológicos na Unidade Básica de Saúde da Família (UBSF) Dom Manoel Pestana Filho. Trata-se de um estudo descritivo. Atécnica utilizada foi a observação direta extensiva por intermédio de questionário. A amostra foi não probabilística, formada por 79 usuários, por acessibilidade, não fazendo uso de forma aleatória de seleção. Apesquisa forneceu informações sobre hábitos de vida e adesão farmacológica e não farmacológica dos pacientes entrevistados. Concluiu-se por meio dos resultados obtidos que a maioria possui HAS e DM, predominando HAS dos tipos I e II. Não se pôde concluir se a adesão do paciente usuário do programa HIPERDIA na UBSF Dom Manoel Pestana Filho é ineficaz ou se a forma de mensuração é falha


The systemic arterial hypertension (SAH) and diabetes mellitus (DM) are characterized as high-impact diseases in Brazilian society. This work aims to identify the adhesion profile of HIPERDIA program's users to pharmacological and non-pharmacological treatments in Unit Basic Family Health Dom Manoel Pestana Filho. This is a descriptive study. The technique used was extensive direct observation through a questionnaire. The sample was non- probabilistic, formed by 79 users, accessibility, not making use of random selection basis. The survey provided information on the patients' habits interviewed and pharmacologic and non-pharmacological adhesion. It was concluded through the results that the majority has SAH and DM, SAH predominantly type I to II. And it can't be concluded whether the adhesion of HIPERDIA's users program in UBSF Dom Manoel Pestana Filho is ineffective or if the form of measurement is flawed.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Diabetes Mellitus , Hypertension
5.
Clinics ; 64(8): 763-767, 2009. ilus, tab
Article in English | LILACS | ID: lil-523995

ABSTRACT

PURPOSE: Establish a relationship between vascular calcifications seen via mammography and coronary artery disease, estimate the risk ratios, and investigate the interrelationships between vascular calcification and other risk factors for coronary artery disease. MATERIALS AND METHODS: This was a case-control study consisting of 40 women with coronary artery disease in the case group and 40 women without any history of coronary artery disease in the control group who were matched according to age. The study was approved by the Institution's Research Ethics Committee (consent statement was obtained). Odds ratios and confidence intervals were calculated using univariate analysis. Interrelationships among other risk factors, such as arterial hypertension, dyslipidemia, smoking and diabetes mellitus, were calculated using multivariate analysis. A p <0.05 was considered to be significant for statistical analysis. RESULTS: The mean ages for the case and control groups were 64.65 years and 63.88 years, respectively. In multivariate analysis, the only variables related to coronary artery disease were Vascular calcification [OR 4.71 (CI 1.36-16.33) p=0.014], family history [OR 5.76 (CI 1.58-21.03) p=0.008] and arterial hypertension [OR 15.92 (CI 3.12-81.14) p=0.001]. Although smoking and diabetes are important variables in the pathogenesis of coronary artery disease, these factors did not show statistically significant associations in this sample. CONCLUSION: The presence of vascular calcifications seen via mammography was an independent risk factor for coronary artery disease, as were hypertension and a family history of coronary artery disease.


Subject(s)
Female , Humans , Middle Aged , Breast Diseases , Calcinosis , Coronary Artery Disease/etiology , Vascular Diseases , Epidemiologic Methods , Family Characteristics , Hypertension/complications , Mammography
6.
Femina ; 36(6): 379-383, jun. 2008. ilus, tab
Article in Portuguese | LILACS | ID: lil-515997

ABSTRACT

A mamografia é um exame complementar de grande importância para o rastreamento do câncer de mama, sendo recomendada prioritariamente para mulhres após os 50 anos. Essa faixa etária também está relacionada a um risco mais alto de desenvolvimento de doença cardiovascular, responsável por altos índices de morbimortalidade entre as mulheres. As calcificações vasculares mamária são freqüentemente vistas nas mamografias, porém ainda não se sabe claramente a patogênese entre as calcificações vasculares mamárias e as doenças coronarianas. Neste trabalho foi feita uma revisão mostrando a ligação epidemiológica existente entre doenças como coronariopatias e diabetes com as calcificações vasculares vistas à mamografia.


Mammography is of great importance for breast cancer screening and is mainly recommended for women older than 50 years old. This age group is also related to a larger risk of development of coronary diseases, which are responsible for the high morbidity and mortality rates among women. The mammary vascular calcifications are frequently seen in mammography, however, so far there is no clear evidence relating the pathogenesis of mammary vascular calcifications and coronary diseases. In this article a literature search was performed showing the epidemiological link between systemic diseases such as coronary diseases and diabetes with mammary vascular calcifications.


Subject(s)
Female , Calcinosis , Diabetes Mellitus/epidemiology , Diabetes Mellitus , Coronary Disease/epidemiology , Coronary Disease , Mammography , Breast Neoplasms/diagnosis , Breast Neoplasms/epidemiology , Breast Neoplasms , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases , Risk Assessment/methods , Risk Factors
7.
Arq. bras. cardiol ; 88(supl.1): 2-19, abr. 2007. tab
Article in Portuguese | LILACS, SES-SP | ID: lil-451704
8.
Rev. ciênc. méd., (Campinas) ; 15(6): 515-524, nov.-dez. 2006. ilus
Article in Portuguese | LILACS | ID: lil-489193

ABSTRACT

A aterosclerose na infância e na adolescência, freqüentemente associada à obesidade, tem sido o foco de estudos internacionais que procuram entender a sua ontogênese. Devido às graves conseqüências possíveis, a aterosclerose na infância e na adolescência não só demanda ações preventivas multidisciplinares capazes de reduzir os fatores de risco já amplamente identificados, como obesidade, hipercolesterolemia familiar, tabagismo e sedentarismo, dentre outros, mas também clama pelo controle de fatores não tão claramente identificados, mas que podem contribuir para a sua patogênese. Dentre as variáveis ainda pouco conhecidas, que poderiam estar envolvidas na ontogênese da aterosclerose, encontram-se os fatores psicológicos e o stress emocional. Neste artigo, os autores versam sobre os aspectos psicológicos envolvidos na prevenção da aterosclerose e enfatizam a necessidade de uma mudança acentuada de estilo de vida, tanto no que se relaciona às atividades físicas e nutricionais como também às relacionadas às medidas anti-stress. Hábitos inadequados utilizados como estratégias de enfrentamento do stress emocional excessivo, como comer em excesso, entre outros, devem ser objeto de medidas preventivas na infância e na adolescência, visando substituí-los por estratégias de coping adequadas que reduzam o risco envolvido. Profissionais da área da saúde devem estar alertas para esses fatores subjacentes que podem contribuir para o desenvolvimento da doença aterosclerótica. Este trabalho foi compilado durante as discussões para a elaboração das I Diretrizes de Prevenção da Aterosclerose na Infância e na Adolescência e serviu de base para as recomendações incluídas na seção denominada "Aspectos Psicológicos na Prevenção da Aterosclerose" das Diretrizes.


Childhood and adolescent atherosclerosis, frequently associated with obesity, has been the focus of international studies that try to understand its development. Given its serious consequences, childhood and adolescent atherosclerosis not only demands multidisciplinary preventive actions that are capable of reducing the already very well identified risk factors, such as obesity, smoking, inactivity and familial hypercholesterolemia - just to mention some - but also calls for the control of factors that have not been clearly identified but that can contribute to its pathogenesis. Psychological factors and emotional stress are among the variables that are not yet fully known but nevertheless could be involved in the development of atherosclerosis. In this article, the authors discuss the psychological aspects involved in the prevention of atherosclerosis and emphasize the need for a dramatic change in lifestyle, which includes changing the levels of physical activity and eating habits and finding ways to fight or avoid stress. Inadequate habits employed as strategies to cope with excessive emotional stress, such as binge eating and others, should be targeted for preventive actions in childhood and adolescence and substituted by adequate coping strategies that have lower levels of risk. Health care professionals need to be watchful for these additional factors that can contribute to the development of atherosclerotic disease. This work was compiled during the discussion phase of the "I Guideline for Preventing Atherosclerosis in Childhood and Adolescence" and served as the basis for the recommendations included in its "Psychological Aspects in Preventing Atherosclerosis" section.


Subject(s)
Humans , Male , Female , Adolescent , Stress, Psychological , Adolescent , Atherosclerosis , Life Style
9.
Arq. bras. cardiol ; 86(3): 240-244, mar. 2006. tab
Article in Portuguese | LILACS | ID: lil-424268

ABSTRACT

OBJETIVOS: Inflamação e ativação das células do sistema imunológico têm participação importante na patogênese da aterosclerose. Este estudo analisa o leucograma que incluiu neutrófilos, eosinófilos, linfócitos, monócitos e basófilos dos pacientes com doença arterial coronariana (DAC) crônica e no infarto agudo do miocárdio (IAM). MÉTODOS: Analisamos o leucograma de 232 pacientes não-diabéticos, com idade entre 15 e 88 anos. A DAC estava presente em 142 pacientes (57 com DAC estável e 85 com IAM), diagnosticada angiograficamente, comparada a 90 indivíduos-controle. Os grupos controle e DAC foram comparáveis para a idade, índice de massa corpórea, antecedentes familiares, tabagismo, hipertensão, HDL e LDL (todas variáveis com p > 0,25). RESULTADOS: A análise univariada mostrou maior prevalência de leucocitose na DAC, sendo maior nos pacientes com IAM quando comparados com a DAC estável. O mesmo comportamento foi observado para os monócitos. Porém, a distribuição foi semelhante para as demais células do hemograma. A análise multivariada pelo método da regressão logística, utilizando-se os modelos stepwise (todas variáveis) e backward (p < 0,25), mostrou que a monocitose foi variável independente para DAC e para o IAM. CONCLUSÃO: O número de monócitos, um dos mais importantes componentes do processo inflamatório na placa aterosclerótica, foi um marcador de risco independente para a DAC e para o IAM.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Biomarkers/blood , Coronary Artery Disease/blood , Leukocytosis/blood , Monocytes , Myocardial Infarction/blood , Atherosclerosis/blood , Chronic Disease , Coronary Artery Disease/etiology , Epidemiologic Methods , Inflammation/blood , Leukocyte Count , Leukocytosis/complications , Myocardial Infarction/etiology
10.
São Paulo; s.n; 2004. [73] p. ilus, tab, graf.
Thesis in Portuguese | LILACS | ID: lil-397904

ABSTRACT

Testar a hipótese de que existe associação entre a contagem sanguínea de células inflamatórias e presença de doença coronariana clinicamente manifesta. Em um modelo de corte transversal, foram estudados 231 indivíduos não diabéticos (155 homens e 76 mulheres, idade 58+-12 anos), selecionados entre abril de 1997 e janeiro de 1998, divididos em 2 grupos: / To try out the hypothesis that there is an association between the inflammatory blood cell count and the presence of clinically manifest coronary disease. In a cross section model, 231 non-diabetic subjects were studied (155 men and 76 women, aged+- 58 12 years old), selected between...


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Coronary Disease/complications , Leukocytosis/etiology , Case-Control Studies , Retrospective Studies , Risk Factors
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